Towards synthetic enzymes
At the Supramolecular Chemistry and Catalysis group, we work towards the integration of biological and chemical processes to generate non-natural conversions in complex media. We explore the exciting opportunities that arise from the integration of polymer chemistry, supramolecular chemistry and stereochemistry with the novel field of bio-orthogonal chemistry, that studies chemical reactions to augment biochemical processes. Using this integrated approach, we focus on the design and synthesis of (supramolecular) copolymers that form nanometer-sized structures with the aim to achieve efficient and selective catalysis in water and in complex cellular media. Developing such complex molecular systems based on non-covalent, reversible interactions, and understanding the mechanisms underlying their formation, will provide a solid foundation to progress towards in vivo applications.
Read moreMeet some of our Researchers
Recent Publications
Our most recent peer reviewed publications
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Effect of Particle Heterogeneity in Catalytic Copper-Containing Single-Chain Polymeric Nanoparticles Revealed by Single-Particle Kinetics
Molecules (2024) -
Effect of Particle Heterogeneity in Catalytic Copper-Containing Single-Chain Polymeric Nanoparticles Revealed by Single-Particle Kinetics
Molecules (2024) -
Backbone-Degradable Acrylate Latex
Macromolecules (2024) -
Enhanced Efficiency of Pd(0)-Based Single Chain Polymeric Nanoparticles for in Vitro Prodrug Activation by Modulating the Polymer’s Microstructure
Nano Letters (2024) -
Bisurea-Based Supramolecular Polymers for Tunable Biomaterials
Chemistry : A European Journal (2024)
Contact
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Visiting address
Helix, STO 4.45Het KranenveldEindhovenNetherlands -
Visiting address
Helix, STO 4.45Het KranenveldEindhovenNetherlands -
Secretarym.jiricka@ tue.nl